PPB

 

PPB

Benign or cancerous tumors seen in the PPB tumor predisposition syndrome include:

  • PPB
  • Lung cysts
  • Cystic nephroma
  • Nodular thyroid hyperplasia/thyroid adenomas
  • Ovarian Sertoli-Leydig tumor, juvenile granulosa cell tumor and gynandroblastoma
  • Embryonal rhabdomyosarcoma
  • Neuroblastoma
  • Wilms tumor
  • Nephrogenic rests
  • Papillary thyroid carcinoma
  • Medulloblastoma and other childhood CNS tumors
  • Nasal chondromesenchymal hamartoma
  • Small bowel polyps (juvenile type/hamartomatous)

Some families may have individuals with one or more of these conditions and no history of PPB. Individuals with any of these conditions may be eligible for the NCI study.

 

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Washington University Barnes Jewish Hospital Siteman Cancer Center
Children's Hospital

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